Where sanctification is enjoined us as our duty, it is prescribed under this notion of cleansing ourselves from sin: “Wash you, make you clean,” Isaiah 1:16. “O Jerusalem, wash thine heart from wickedness, that thou mayest be saved,” Jeremiah 4:14. “Having therefore these promises, let us cleanse ourselves from all filthiness of the flesh and spirit, perfecting holiness in the fear of God”…
Nothing do they more earnestly labor after in their prayers and supplications than a cleansing from it by the blood of Christ, nor are any promises more precious unto them than those which express their purification and purging from it; for these are they which, next unto their interest in the atonement made by the sacrifice of Christ, give them boldness in their approaches unto God. So our apostle fully expresseth it, Hebrews 10:19-22: “Having therefore boldness to enter into the holiest by the blood of Jesus, by a new and living way, which he hath consecrated for us, through the veil, that is to say, his flesh; and having an high priest over the house of God; let us draw near with a true heart in full assurance of faith, having our hearts sprinkled from an evil conscience, and our bodies washed with pure water…”
—John Owen, Pneumatologia (HT: Jack Miller)